Evaluation of the Effect of Titatnium Dioxide Nanoparticles/Gelatin Composite on Infected Skin Wound Healing; An Animal Model Study

Amin Nikpasand; mohammad reza parvizi

Volume 7, Issue 4 , October 2019, , Pages 366-372

  Objective: To evaluate effects of titanium dioxide /gelatin nanocomposite on wound healing in mice as a model study. Methods: Fifty male rats were randomized into five groups of ten animals each. In group I, 0.1 mL sterile saline 0.9% solution was added to the wounds with no infection.  In group ...  Read More

Effects of Chitosan/Nano Selenium Biofilm on Infected Wound Healing in Rats; An Experimental Study

Abolfazl Abbaszadeh; Akram Tehmasebi-Foolad; Asghar Rajabzadeh; Nasim Beigi-Brojeni; Leila Zarei

Volume 7, Issue 3 , July 2019, , Pages 284-291

  Objective: The present study was aimed at assessment of effect of application of Chitosan/Nano Selenium biofilm on infected wound healing in ratsMethods: Sixty-eight male Wistar rats were randomized into four groups of 17 animals each. In group I (Normal) the wounds were created with no infection. In ...  Read More

Curcumin and Nanocurcumin Oral Supplementation Improve Muscle Healing in a Rat Model of Surgical Muscle Laceration

Siamak Kazemi-Darabadi; Ramin Nayebzadeh; Amir Ali Shahbazfar; Faranak Kazemi-Darabadi; Ezzatollah Fathi

Volume 7, Issue 3 , July 2019, , Pages 292-299

  Objective: To compare the effects of curcumin and nanocurcumin oral supplementation on the muscle healing rate of an animal model of surgical muscle laceration.Methods: Thirty-two male adult rats were randomly divided into sham, control, curcumin, and nanocurcumin groups. Partial transection of the gastrocnemius ...  Read More

The Effects of Chicken Embryo Brain Extract on Sciatic Nerve Regeneration of Male Rat; An Experimental Study

Fatemeh Rasouli-Sangani; Gholam Hossein Farjah; Sima Nasry

Volume 6, Issue 3 , July 2018, , Pages 201-206

  Objective: To determine the effects of chicken embryo brain extract (BE) on transects sciatic nerve in male rats.Methods: Thirty adult male Sprague-Dawley rats weighing 200 to 250 g, were randomized into three groups treated with (1) sham surgery, (2) normal saline (NS), and (3) brain extract (BE). The ...  Read More

Effects of Aloe Vera and Chitosan Nanoparticle Thin-Film Membranes on Wound Healing in Full Thickness Infected Wounds with Methicillin Resistant Staphylococcus Aureus

Reza Ranjbar; Alireza Yousefi

Volume 6, Issue 1 , January 2018, , Pages 8-15

  Objective: To assess effect of Aleo vera with chitosan nanoparticle biofilm on wound healing in full thickness infected wounds with antibiotic resistant gram positive bacteria.Method: Thirty rats were randomized into five groups of six rats each. Group I: Animals with uninfected wounds treated with 0.9% ...  Read More

Assessment of Neuroprotective Effects of Local Administration of 17- Beta- Estradiol on Peripheral Nerve Regeneration in Ovariectomized Female Rats

Ahmadreza Nobakhti-Afshar; Alireza Najafpour; Rahim Mohammadi; Leila Zarei

Volume 4, Issue 3 , July 2016, , Pages 141-149

  Objective: To assess the neuroprotective effects of local administration of 17- beta- estradiol on nerve regeneration.Methods: Sixty female Wistar rats were overiectomized and divided into four experimental groups (n = 15), randomly: In autograft group a segment of sciatic nerve was transected and re-implanted ...  Read More

Effects of Intraperitoneal Administration of Simvastatin in Prevention of Postoperative Intra-abdominal Adhesion Formation in Animal Model of Rat

Mojtaba Javaherzadeh; Ali Shekarchizadeh; Marjan Kafaei; Abass Mirafshrieh; Nariman Mosaffa; Babak Sabet

Volume 4, Issue 3 , July 2016, , Pages 156-160

  Objective: To determine the preventive effects of local administration of simvastatin for postoperative intra-abdominal adhesion formation in animal model of rat.Methods: In this experimental study, 32 Wistar albino rats as the animal model of intra-abdominal adhesion formation were included. Adhesions ...  Read More

The Effects of Oltipraz on Tissue Regeneration in the Process of Wound Healing: A Stereological Study

Ali Noorafshan; Sina Kardeh; Soheil Ashkani-Esfahani; Mohammadreza Namazi; Ehsan Saleh

Volume 2, Issue 4 , October 2014, , Pages 161-165

  Objective: To determine the effects of topical administration of 20% oltipraz solution on histomorphometrical and stereological aspects of skin tissue in full thickness skin wounds in laboratory rats.Methods: Thirty-six male Wistar portion rats (220±20 g) were randomly divided into three groups (n=12). ...  Read More