Scorpion bite has different manifestations in vital organs and may cause blindness secondary to involvement in the circulation of these vital organs. We report a case of abrupt vision loss and periorbital edema and redness due to scorpion bite in the eyebrow in an endemic region of southern Iran. A 45-year-old woman referred to the emergency room of our ophthalmology center due to abrupt vision loss and periorbital edema in her right eye. Involvement of ocular vasculature by localizing stroke due to the coagulative disorder caused by scorpion venom leads to retinal vein occlusion in this case. Management of BRVO was done with intravitreal injection of bevacizumab in the early phase. The outcome was complete vision recovery. To the best of our knowledge, this is the first case of macular branch retinal vein occlusion after scorpion bite.