Original Article
Hamidreza Shetabi; hossein Mahjoubipour; mona bahmani
Volume 12, Issue 1 , January 2024, Pages 1-7
Abstract
Objective: This study aimed to assess and compare the effects of intranasal administration of lidocaine andremifentanil on the condition of LMA insertion and cardiovascular response.Methods: From March 2019 to March 2020, this double-blind randomized clinical trial study was conductedon 60 patients, ...
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Objective: This study aimed to assess and compare the effects of intranasal administration of lidocaine andremifentanil on the condition of LMA insertion and cardiovascular response.Methods: From March 2019 to March 2020, this double-blind randomized clinical trial study was conductedon 60 patients, who underwent general anesthesia with LMA insertion at Faiz Hospital, Isfahan, Iran. Afterinduction of anesthesia and before placing the laryngeal mask, the first group received remifentanil 1 μg/Kg,the second group received lidocaine 2% 1 mg/Kg, and the third group received normal saline with the samevolume intranasally. The conditions of LMA insertion and hemodynamic changes that occurred during itsinsertion were investigated.Results: In terms of demographics characteristics (p>0.05), success in placing the LMA on the first try(p=0.73), number of attempts to insert LMA (p=0.61), performance of LMA (p=0.73), need for additionalpropofol (p=0.53), frequency of gagging (p=0.53), cough (p=0.15) p), and laryngospasm (p=0.99) did notdiffer significantly. In the remifentanil group, the cardiovascular response to LMA injection was less than thatof the lidocaine group. Moreover, both groups were lower than the saline group, but no significant differencewas observedConclusion: In facilitating LMA insertion, the effect of intranasal remifentanil was comparable to intranasallidocaine. Intranasal remifentanil was somewhat more effective than intranasal lidocaine in weakening thecardiovascular response to LMA insertion, but it did not outperform lidocaine.
Original Article
Elham Pishbin; Maryam Ziyaei; elnaz vafadar moradi; Mohsen Foroughipour; Rahim Javadzadeh; Mahdi Foroughian
Volume 12, Issue 1 , January 2024, Pages 8-14
Abstract
Objective: Cerebral Venous Sinus Thrombosis (CVST), a complex and infrequent cerebrovascular disordercharacterized by the formation of clots within the cerebral venous sinuses, occurs as a result of multiple riskfactors and casualties, and its epidemiological picture should be investigated.Methods: This ...
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Objective: Cerebral Venous Sinus Thrombosis (CVST), a complex and infrequent cerebrovascular disordercharacterized by the formation of clots within the cerebral venous sinuses, occurs as a result of multiple riskfactors and casualties, and its epidemiological picture should be investigated.Methods: This descriptive study was conducted retrospectively on patients with a final diagnosis of cerebralvein thrombosis, who were referred to the emergency room of Ghaem Hospital (Mashhad, Iran) between 2009and 2019. The study included all patients with cerebral vein thrombosis who were older than 18 years. Clinicalsymptoms and causes were documented and contrasted according to demographics.Results: During the 10 years of this study, 749 cases of cerebral vein thrombosis were observed, with womenaccounting for the majority (72.8%). The most prevalent symptom was headache (554 cases; 74.0%), followedby seizures (23.1%), blurred vision (16.0%), nausea (7.5%), vomiting (6.9%), double nose (4.9%), and dizziness(3.3%). There was no significant difference in the frequency of symptoms between the two genders (p<0.05). Themost commonly identified risk factors were OCP (110 cases; 14.7%), followed by infection (103 cases; 13.8%),malignancies (78 cases; 10.4%), and fasting (15 cases; 2.0%). There was no significant difference in risk factorsbetween the two genders, with the exception that all cases of fasting were in women, and the differences weresignificant (p=0.015). The most common site of involvement according to Magnetic Resonance Venography(MRV) was the upper sagittal sinus (427 cases; 57.0%). There was no significant difference in terms of the siteof the conflict between the two genders (p<0.05).Conclusion: The findings of the present study showed that deep vein thrombosis occurred mainly in womenand manifested itself mostly as a headache. Moreover, the upper sagittal sinus was the most common site ofinvolvement.
Original Article
Reza Eshraghi; Sina Shamsi; Masoumeh safaee
Volume 12, Issue 1 , January 2024, Pages 15-20
Abstract
Objective: This study aimed to evaluate the outcome and risk factors in operative and non-operativemanagement of splenic injury.Methods: This cross-sectional study was conducted on patients with traumatic splenic injuries who werehospitalized in Kashani Hospital (Isfahan, Iran) from 2017 to 2019. The ...
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Objective: This study aimed to evaluate the outcome and risk factors in operative and non-operativemanagement of splenic injury.Methods: This cross-sectional study was conducted on patients with traumatic splenic injuries who werehospitalized in Kashani Hospital (Isfahan, Iran) from 2017 to 2019. The studied variables were extracted fromthe medical records of the enrolled participants. The outcomes such as mortality complications and risk factorswere compared based on treatment methods.Results: A total of 240 patients were investigated. The mean age of the patients was 29.8±12.2, with 180(77.5%) patients being men. 154 (64.2%) patients underwent operative treatment. The mortality rate was 18.9%and 4.6% among operative and non-operative groups (p<0.001). Complications were observed in 11.5% and46.1% of non-operative and operative groups, respectively (p<0.001). Operative treatment inversely correlatedwith mortality (p<0.001) and complications (p<0.05). Splenic injury severity was correlated positivelywith mortality (p<0.001) and negatively with complications (p<0.001). Unstable hemodynamic status waspositively correlated with complications (p<0.001). Age had a positive correlation with mortality (p<0.001)and complications (p<0.001). Male sex had a negative correlation with complications (p<0.001). GCS score andadmission were positively correlated with mortality (p<0.001). There was no statistically significant correlationbetween correlated injuries and outcomes (p≥0.05).Conclusion: Patients who received surgery had higher rates of mortality and complications. However, aftercontrolling for confounders, operative treatment was found to be inversely correlated with mortality andcomplications.
Original Article
Seyed Mostafa Mirakbari; Amir Mohammad Kazemifar; Abbas Allami; Ameneh Barikani
Volume 12, Issue 1 , January 2024, Pages 21-25
Abstract
Objective: This study aimed to investigate the incidence and pattern of tramadol-induced seizures and injuriesin patients admitted to the hospital.Methods: The cross-sectional study included 300 patients with alleged tramadol intoxication. Demographicinformation, tramadol dosage and duration of abuse, ...
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Objective: This study aimed to investigate the incidence and pattern of tramadol-induced seizures and injuriesin patients admitted to the hospital.Methods: The cross-sectional study included 300 patients with alleged tramadol intoxication. Demographicinformation, tramadol dosage and duration of abuse, co-existing illicit drug abuse, hospital stay length, andoccurrence of seizures and trauma (type and site of injuries) were collected. Different statistical tests, includingthe Mann-Whitney U-test, Pearson’s Chi-square test, and Student’s t-test, were conducted to compare thepatients with and without seizures, trauma, and co-ingestion of illicit drugs. The analysis was performed usingSPSS software (version 21.0). A p value of less than 0.05 was considered statistically significant.Results: The average patient’s age was 24.66±5.64 years, with males comprising 84.3% of the sample. Themean tramadol dose and duration of abuse were 1339.3±1310.2 mg and 2.43±1.35 years, respectively. Seizureswere observed in 66% of patients, with men having a higher incidence (69.6% vs. 46.8%; p=0.004). Trauma wasreported in 23% of patients, accounting for 35.4% of seizure cases. All trauma patients had experienced seizures,with the head and neck being the most prevalent injury sites (55.1%), typically presenting as abrasions (55.9%).Patients with seizures and trauma had an average hospital stay of 1.73±0.94 days, which was significantlylonger.Conclusion: Trauma occurs in more than one-third of tramadol-induced seizures, highlighting the needto perform physical examinations to detect and localize injuries. Tramadol-associated traumas prolongedhospitalization times and thus required prompt attention to prevent further injuries during pre-hospital handlingand transferring to hospitals.
Original Article
Mehran Kouchek; kamran Aghakhani; Mostafa Dahmardehei; Azadeh Memarian
Volume 12, Issue 1 , January 2024, Pages 26-34
Abstract
Objective: This study investigated the demographic characteristics and factors influencing burn injuries,primarily in low socioeconomic societies where such incidents are prevalent due to factors such as illiteracyand poverty.Methods: This cross-sectional study included all burn patients admitted to ...
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Objective: This study investigated the demographic characteristics and factors influencing burn injuries,primarily in low socioeconomic societies where such incidents are prevalent due to factors such as illiteracyand poverty.Methods: This cross-sectional study included all burn patients admitted to Shahid Motahari Hospital inTehran, Iran. Demographic data such as age, sex, occupation, education level, and residence as well as detailedinformation about the burn incidents such as date, time, location, number of people present at the scene, andreferral place was collected. Additionally, comprehensive burn details such as cause, extent, severity, previoushistory, and need for hospitalization directly at the emergency department were documented.Results: The study included 2213 patients (mean age 34.98±19.41 years; range 1-96), with a men predominance(60.6%). The majority of burns (64.4%) occurred at home, primarily due to accidents (99.6%), with boilingwater being the most common cause (39.2%). The most frequent burns were second-degree burns (91.8%),with an average injured body area of 6.31±6.67%. There were significant correlations between burn severityand demographic factors such as age, sex, occupation, cause of burn, hospital admission, outcome, and lengthof stay. Remarkably, the extent of burns was negatively correlated with the distance to the hospital, whilepositively correlated with the length of hospital stay.Conclusion: Burn injuries were significantly influenced by demographic factors. Enhancing treatment facilitiesand reducing the time and distance to medical care could be crucial in high-risk cases.
Original Article
Sayed Reza Ahmadi; Maliheh Ziaee; Humain Baharvahdat; Zahra Ahmadi; Morteza Talebi delouee; Behrange Rezvani Kakhki; Mohammad Salehi kareshk; Elnaz Vafadar Moradi
Volume 12, Issue 1 , January 2024, Pages 35-41
Abstract
Objective: Subarachnoid hemorrhage (SAH) is still considered a life-threatening medical condition witha high mortality rate, particularly in developing countries. Thus, the present study aimed to investigate theangiographic findings of non-traumatic or spontaneous SAH.Methods: This retrospective cohort ...
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Objective: Subarachnoid hemorrhage (SAH) is still considered a life-threatening medical condition witha high mortality rate, particularly in developing countries. Thus, the present study aimed to investigate theangiographic findings of non-traumatic or spontaneous SAH.Methods: This retrospective cohort study included 642 health records of patients with non-traumatic SAH overa 10-year period, from 2010 to 2020. The required data, including demographic information, aneurysm type,size, location, disease severity classification, and secondary complications, were extracted.Results: The study included 642 patients, with 262 (40.8%) being male. The mean age of the participants was54.72±13.51 years. The most prevalent type of aneurysm was saccular (89.1%), while serpentine (0.2%) anddissecting saccular (0.2%) aneurysms had the least prevalence. The most frequently involved arteries were theanterior communicating artery (ACoA; 38%), internal carotid artery (ICA; 27.6%), and middle cerebral artery(MCA; 13.4%). There was a significant correlation between sex and aneurysms occurring at ACoA and ICA(p< 0.0001), and ACoA – A1 (p=0.02). Patient age and sex were also significantly correlated with one another(p<0.0001). There was no statistically significant correlation between sex, aneurysm size, Glasgow coma scale(GCS), and modified Rankin scale (MRS).Conclusion: Based on our findings, the presence of aneurysms at ACoA, ACoA – A1, and ICA should bethoroughly ruled out in patients with severe headaches of sudden onset, particularly male patients of youngerages.
Case Report
Mohammad Sadegh Masoudi; Sina Zoghi; Adrina Habibzadeh; Reza Taheri; Ali Ansari
Volume 12, Issue 1 , January 2024, Pages 42-45
Abstract
Approaching posterior fossa pathologies is fairly challenging. Poor exposure, Cerebrospinal Fluid (CSF) leak following surgery, post-operative suboccipital and neck pain, and wound healing are common challenges following traditional suboccipital midline incision. Herein, we present a new incision for ...
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Approaching posterior fossa pathologies is fairly challenging. Poor exposure, Cerebrospinal Fluid (CSF) leak following surgery, post-operative suboccipital and neck pain, and wound healing are common challenges following traditional suboccipital midline incision. Herein, we present a new incision for approaching posterior fossa pathologies. The incision is shaped like a question mark and makes a musculofascial flap supplied by occipital artery on top of providing a wide area for craniotomy. In our technique, the dura is also incised in a question mark shaped manner. Three patients with masses in posterior fossa were operated with the new incision. Following surgeries, there were no adverse events including CSF leak, wound complications, severe suboccipital pain and neck instability in any of the patients. This new incision not only facilitates approaching to pathologies in posterior fossa with providing wider exposure, but also enables us for watertight Dural closure which decreases CSF leak. Also, as the muscular incision provides a sufficient area for craniotomy, muscular retraction can be minimized to avoid post-operative pain. Moreover, as opposed to the midline avascular incision, the flap is well supplied by occipital artery which facilitates the healing procedure.
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