Document Type : Original Article
Authors
- Siamak Rimaz 1
- Vahideh Abdi 1
- Cyrus Emir Alavi 2
- Sanaz Masoumi 3
- Mahsa Sadeghi 1
- Mohammadreza Mobayen 3
- Parissa Bagheri 4
1 Burn and Regenerative Medicine Research Center, Guilan University of Medical Sciences, Rasht, Iran.
2 Razi Clinical Research Development Unit, Guilan University of Medical Sciences, Rasht. Iran.
3 Burn and Regenerative Medicine Research Center, Guilan University of Medical Sciences, Rasht, Iran
4 Medical Education Research Center, Education Development Center, Guilan University of Medical Sciences, Rasht, Iran
Abstract
Objective: Burn injuries are a significant public health concern, contributing substantially to morbidity and mortality rates. Mechanical ventilation (MV) is crucial in managing critically ill patients with extensive burns. This study aimed to determine the survival rate of burn patients under mechanical ventilation and identify the risk factors related to it.
Methods: A cross-sectional analytical study was conducted at Velayat Hospital, affiliated with Guilan University of Medical Sciences, between March 21, 2011, and September 21, 2020. Data were retrieved from electronic hospital records and analyzed using SPSS version 28.
Results: The mean age of survivors was 19.03±30.21 years, contrasting with 42.54±19.30 years in the deceased group. Among survivors, 30 were male (78.9%), while in the deceased group, 155 were male (64.9%). The average survival time in the intensive care unit was 18.33±1.36 days, with a median survival of 12±1.24 days. Significant differences were observed in age, length of stay, comorbidity, inhalation injury, sepsis, acute respiratory distress syndrome (ARDS), and acute kidney injury (AKI) between survivor and non-survivor groups (P<0.05). The Kaplan-Meier curve demonstrated a significant difference in survival probability between MV and non-MV groups (P=0.028), with higher survival probability observed in non-MV patients.
Conclusion: Our findings indicate that factors such as age, length of stay, renal failure, ARDS, and sepsis are associated with increased mortality risk in mechanically ventilated burn patients. While these associations provide critical insights into potential risk factors, they should not be interpreted as causal relationships. Future research should explore these associations through interventional or longitudinal studies to establish causality and refine treatment strategies.
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