Faramarz Dobakhti; Ali Zargar; Taraneh Naghibi
Volume 11, Issue 1 , January 2023, , Pages 26-31
Abstract
Objective: Ventilator-associated pneumonia is the common cause of morbidity and mortality in the intensivecare unit. Due to the antimicrobial effect of chlorhexidine, and the long-lasting result of mucoadhesive drugs,this study aimed to determine the effect of chlorhexidine mucoadhesive gel on the prevention ...
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Objective: Ventilator-associated pneumonia is the common cause of morbidity and mortality in the intensivecare unit. Due to the antimicrobial effect of chlorhexidine, and the long-lasting result of mucoadhesive drugs,this study aimed to determine the effect of chlorhexidine mucoadhesive gel on the prevention of ventilatorassociatedpneumonia in critical patients.Method: In this clinical trial, 64 ventilated patients were selected and randomly allocated into two groups. Thefirst group received 0.2% chlorhexidine mucoadhesive gel and the second group received 0.2% chlorhexidinesolution as a mouthwash. Every three days, the incidence of ventilator-associated pneumonia was evaluatedby the clinical score of pulmonary infection. The data were analyzed by SPSS statistical software version 20.Results: There was no statistically significant difference in demographic characteristics between the twogroups. In the control group, 25% of the patients had ventilator-associated pneumonia, while it was only 15.6%in the intervention group; however, the incidence of ventilator-associated pneumonia revealed no significantdifference between the two groups (HR ratio, 0.86; 95% confidence interval, 0.49 to 1.83 p=0.356).In addition,there was no statistically significant difference between the number of days connected to the ventilator(p=0.854), the number of days hospitalized in the intensive care unit (p=0.423), and the death rate (p=0.634)between the two groups.Conclusion: Although no significant statistical difference was detected between chlorhexidine mucoadhesivegel and chlorhexidine solution in the prevention of ventilator-associated pneumonia, the incidence of pneumoniain the mucoadhesive gel group was clinically less than in the control group. It is better to repeat the study witha larger statistical population.
Hossein Abdolrahimzadeh fard; Roham Borazjani; Amir Hossein Shams; Vala Rezaee; Shiva Aminnia; Maryam Salimi; Mahsa Ahadi; Shahram Paydar; Shahram Bolandparvaz; Nikta Rabiei; Sanaz Zare; Leila Shayan; Mina Sadeghi
Volume 10, Issue 3 , July 2022, , Pages 128-134
Abstract
Objective: To evaluate the presence/severity of depression, anxiety, and stress among health care workers(HCWs) who work on the specially allocated COVID-19 ward (Group A) and HCWs on the other wards(Group B).Methods: This questionnaire-based study was conducted from January 25 to February 28, 2021. ...
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Objective: To evaluate the presence/severity of depression, anxiety, and stress among health care workers(HCWs) who work on the specially allocated COVID-19 ward (Group A) and HCWs on the other wards(Group B).Methods: This questionnaire-based study was conducted from January 25 to February 28, 2021. The mentalstatus was assessed using the Persian version of the 42-item Depression, Anxiety, and Stress score (DASS-42).Gathered data was analyzed using SPSS version 25. The independent T-test and Chi-square tests were used tocompare quantitative and qualitative variables.Results: Two-hundred and twenty two questionnaires were eligible for analysis. Group A consisted of 33HCWs, and 189 (85.1%) individuals were working on the other wards. No statistically significant differenceswere seen regarding the Socio-demographic features except for the marital status (p=0.005). The depressions’mean score was comparable between group A and B (p=0.102). The mean scores of anxiety and stress weresignificantly lower in group A than group B (p=0.006), although the frequency of DASS-42 parameters did notdiffer between these two groups (p>0.05).Conclusion: Contrary to our assumptions, this study showed that the DASS-42 parameters were not higher inHCWs working on the COVID-19 wards. This might be justified by developing coping mechanisms, being onthe honeymoon phase of the disaster, compassion satisfaction, promising vaccine news, and working on theless impacted hospital.
Nguyen Nguyen The Phung; Trang Thi Thanh Vo; Kam Lun Ellis Hon
Volume 8, Issue 2 , April 2020, , Pages 121-124
Abstract
The aim of the current study was to describe lung ultrasonography (LUS) characteristics and to evaluate the agreement between LUS and chest radiography (CXR) in diagnosis of four conditions causing most acute dyspnea in children, namely, pneumonia, pleural effusion, pneumothorax and acute pulmonary edema ...
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The aim of the current study was to describe lung ultrasonography (LUS) characteristics and to evaluate the agreement between LUS and chest radiography (CXR) in diagnosis of four conditions causing most acute dyspnea in children, namely, pneumonia, pleural effusion, pneumothorax and acute pulmonary edema in children at a teaching hospital in Vietnam. We reviewed the records of the chidren between January and June 2018, who presented to emergency department (ED) or pediatric intensive care unit (PICU) at children hospital 1 (CH1) with acute dyspnea and had final diagnosis of one of four etiologies including pneumonia, pleural effusion, pneumothorax and acute pulmonary edema. All patients underwent CXR and LUS at the time of admission. Eighty-one children with acute dyspnea including pneumonia (n=65, 80%), pleural effusion (n=9, 11%), pneumothorax (n=3, 4%) and acute pulmonary edema (n=4, 5%) were enrolled. LUS was identified among 100% of cases with pleural effusion and pneumothorax (CXR only showed 73.3% and 50%, respectively); 92.3% of cases with pneumonia (CXR showed 93.8%) and only 75% of cases with acute pulmonary edema (CXR showed 50%). When comparing LUS with CXR, we noticed a good agreeement between the 2 methods in the diagnosis of pneumonia (kappa=0.64, p<0.001). LUS was shown to be a feasible and non-invasive technique which can help clinicians to comfirm the etiology of acute pulmonary dyspnea.
