Omid Yousefi; Shahab Ghazi Mirsaiid; Pouria Azami; Ghazal Karimi; Arash Mani; Amin Niakan; Hosseinali Khalili
Volume 10, Issue 4 , October 2022, , Pages 157-164
Abstract
Objective: To study a Boswellia and ginger mixture on the memory dysfunction of the mild traumatic braininjury (mTBI) patients.Methods: Patients with mTBI were asked about memory impairment following the injury. One hundred mTBIpatients were visited and assessed using an auditory-visual learning test ...
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Objective: To study a Boswellia and ginger mixture on the memory dysfunction of the mild traumatic braininjury (mTBI) patients.Methods: Patients with mTBI were asked about memory impairment following the injury. One hundred mTBIpatients were visited and assessed using an auditory-visual learning test (AVLT) questionnaire. By usingrandom permuted blocks, patients were given the Memoral (a mixture of 360 mg of Boswellia and 36 mg ofginger) or placebo and were asked to consume it for a month. Patients were assessed one and three monthsafterward using the second and third steps of AVLT, respectively.Results: One hundred patients were included in the study and divided into control and intervention groups.The mean age of the patients was 36.83±14.71, and there were no significant differences between the twogroups (p=0.41). There were no statistically significant differences in the baseline scores of different AVLTparameters between the two groups. All patients had improvements in different parameters after three months.But some factors include the scores’ change in total learning, retroactive interference score, forgetting rate,and net positive score were significantly higher in treatment groups at one-month and three-month follow-upscompared to the placebo group. In contrast, word span and hit parameters had the same pattern of improvementin both groups.Conclusion: The herbal medication can have a satisfactory effect on eliminating post-mTBI memory dysfunctionwhile having no considerable adverse effects. The effect of these components can also be sustained after a twomonthtimeframe. These results may assist patients to have less mental involvement.
Hosseinali Khalili; Amin Niakan; Fariborz Ghaffarpasand
Volume 4, Issue 4 , October 2016, , Pages 248-249
Hosseinali Khalili; Aydin Omidvar; Fariborz Ghaffarpasand; Golnaz Yadollahikhales
Volume 4, Issue 1 , January 2016, , Pages 24-28
Abstract
Objective: To determine the effects of application of anti-adhesive films (OrthoWrap™) in traumatic decompressive craniectomy on prevention of adhesion formation and facilitation of subsequent cranioplasty.Methods: This was a retrospective cohort study being performed in Shahid Rajaei hospital (Shiraz ...
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Objective: To determine the effects of application of anti-adhesive films (OrthoWrap™) in traumatic decompressive craniectomy on prevention of adhesion formation and facilitation of subsequent cranioplasty.Methods: This was a retrospective cohort study being performed in Shahid Rajaei hospital (Shiraz Level I trauma center) during a 12-month period (from March 2012 to April 2013) including 93 patients undergoing traumatic decompressive craniectomy. Patients who received OrthoWrap™ during the initial craniectomy (n=44) were compared to those who did not (n=49). Two study groups were matched regarding the baseline characteristics. The perioperative indices including the surgical time, amount of bleeding, transfusion and 6-month Glasgow Outcome Scale (GOS) were compared between two study groups.Results: There was no significant difference between two study groups regarding the baseline characteristics. We found that the cranioplasty duration (113.3±33.2 vs. 146.9±34.9 minutes; p<0.001) and amount of intraoperative bleeding (182.1±98.3 vs. 270.6±77.6 mL; p=0.043) was significantly lower in those who had OrthoWrap™ compared to control group. The final GCS (p=0.052) as well as GOSE (p=0.653) was comparable between groups. The infection rate was comparable between two study groups (p=0.263).Conclusion: Application of OrthoWrap™ during decompressive craniectomy in those with severe traumatic brain injury is associated with shorter duration of operation and less intraoperative bleeding in subsequent cranioplasty. Infection rate and neurologic outcome was comparable between study groups.
