Seyed Mohammad Hosseininejad; Farzad Bozorgi; Seyyed Hosein Montazar; Reza Ali Mohammadpour; Gholamhossein Hajiaghaei
Volume 11, Issue 3 , July 2023, , Pages 119-124
Abstract
Objective: To investigate the use of prognostic markers such as C-reactive protein (CRP) and D-dimer forclinical outcomes in patients with mild traumatic brain injury (TBI).Methods: This cross-sectional study was conducted on patients with mild head trauma who were admittedto the Emergency Department ...
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Objective: To investigate the use of prognostic markers such as C-reactive protein (CRP) and D-dimer forclinical outcomes in patients with mild traumatic brain injury (TBI).Methods: This cross-sectional study was conducted on patients with mild head trauma who were admittedto the Emergency Department of Imam Khomeini Hospital (Sari, Iran). Data were collected from 2018 to2019. Age, sex, the time of injury hospitalization, length of hospitalization, length of unconsciousness, bloodpressure, heart rate, respiratory rate, and concomitant symptoms were all recorded using a pre-designedchecklist. The patient’s Glasgow Coma Scale (GCS), CRP, and D-dimer were also measured. Moreover, allpatients underwent CT scan.Results: This study included 74 patients with TBI. The mean age of the participants was 36.92±3.54. Themean CRP and D-dimer values were 5.69±0.77 and 0.58±0.11 in these patients, respectively. At the cut-offpoint of 11.50 for CRP, the sensitivity and specificity to detect the pathological lesions in CT scan was 75%and 95.50%, respectively (p<0.001). Additionally, with a D-dimer cut-off point of 0.90, the sensitivity andspecificity for diagnosing pathological lesions in CT scan were 100% and 98.50%, respectively (p<0.001).Conclusion: In general, the CRP and D-dimer levels of patients with mild TBI (GCS≥13) can be assessed toprotect against CT-induced radiation exposure and subsequent disorders; if they do not exhibit clinical signs toincrease the risk of adverse brain damage, such as reduced level of consciousness, drowsiness, and prolongedperiods of unconsciousness.
Rohit Bharti; Sindhu Sapru; Ponraj Kamatchi Sundaram; Ganesh Chauhan
Volume 9, Issue 4 , October 2021, , Pages 188-194
Abstract
Objective: To evaluate the impact of the early tracheostomy on operated patients with severe head injury. Methods: This prospective observational study was conducted at a level 1 trauma center and medical college over one-year period. The study included all surgically managed severe head injury patients ...
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Objective: To evaluate the impact of the early tracheostomy on operated patients with severe head injury. Methods: This prospective observational study was conducted at a level 1 trauma center and medical college over one-year period. The study included all surgically managed severe head injury patients without any other life-threatening major injuries. Patients who underwent tracheostomy within 7 days were classified as early tracheostomy. Results: The patient’s mean age of this cohort study was 43.4±14.5 years. Motor-vehicle accidents were being the most common cause of severe head injury. Operated patients were undergoing early tracheostomy on an average of 2.9 days. We were observed that the patients spent on a mechanical ventilation on an average 3.67±2.26 days. This was significantly lower than previous four published studies (p <0.05) which had a range of mean 9.8-15.7 days. Conclusion: We have shown that it is possible to decrease mechanical ventilation (MV) time, intensive care unit (ICU) stay and total hospital stay by doing early tracheostomy in operated severe head injury patients.
Mohamadreza Saatian; Jamal Ahmadpoor; Younes Mohammadi; Ehsan Mazloumi
Volume 6, Issue 1 , January 2018, , Pages 45-53
Abstract
Objective: To determine the epidemiological aspects of patients with traumatic brain injury (TBI) in a regional trauma center.Methods: A cross-sectional study was conducted on patients with TBI during 2013 to 2016 in a single center in Hamedan, central Iran. The distribution and relationships of TBI ...
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Objective: To determine the epidemiological aspects of patients with traumatic brain injury (TBI) in a regional trauma center.Methods: A cross-sectional study was conducted on patients with TBI during 2013 to 2016 in a single center in Hamedan, central Iran. The distribution and relationships of TBI was assessed with gender, age, type of trauma, traumatic cause, exiting status and Length of Hospitalization (LOH). Data were analyzed by Stata V11 statistical software.Results: In general, 9426 patients with TBI were enrolled in analyses. The mean ± SD age of patients was 29.70 (± 21.46) years. Multivariate logistic regression indicated that being male [OR: 1.29; 95% CI (2.92-4.73), P ≤0.001], 41-50 to 71-80 and 90+ years old' age groups (1.32<OR<3.12, 0.029<p≤0.001), having surgery [OR: 5.58; 95% CI (4.89-6.37), p≤0.001], and different types of trauma (p≤0.001) were significantly related to LOH. Moreover, odds ratio of mortality was 1.52 times greater in males than females (p≤0.001). As the age increases, the odds ratio of mortality was also rising. However, having surgery [OR: 3.72; 95% CI (2.92-4.73), p≤0.001], LOH >5 days [OR: 2.01; 95% CI (1.60-2.52), p≤0.001] and different types of trauma were significantly related to mortality.Conclusion: TBI is one of the main causes of mortality and LOH of the young population. By providing preventive measures and a traumatic care system, the burden of trauma can be greatly reduced, the implementation of the trauma care system in Hamedan province is a necessity.
