Omid Yousefi; Shahab Ghazi Mirsaiid; Pouria Azami; Ghazal Karimi; Arash Mani; Amin Niakan; Hosseinali Khalili
Volume 10, Issue 4 , October 2022, , Pages 157-164
Abstract
Objective: To study a Boswellia and ginger mixture on the memory dysfunction of the mild traumatic braininjury (mTBI) patients.Methods: Patients with mTBI were asked about memory impairment following the injury. One hundred mTBIpatients were visited and assessed using an auditory-visual learning test ...
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Objective: To study a Boswellia and ginger mixture on the memory dysfunction of the mild traumatic braininjury (mTBI) patients.Methods: Patients with mTBI were asked about memory impairment following the injury. One hundred mTBIpatients were visited and assessed using an auditory-visual learning test (AVLT) questionnaire. By usingrandom permuted blocks, patients were given the Memoral (a mixture of 360 mg of Boswellia and 36 mg ofginger) or placebo and were asked to consume it for a month. Patients were assessed one and three monthsafterward using the second and third steps of AVLT, respectively.Results: One hundred patients were included in the study and divided into control and intervention groups.The mean age of the patients was 36.83±14.71, and there were no significant differences between the twogroups (p=0.41). There were no statistically significant differences in the baseline scores of different AVLTparameters between the two groups. All patients had improvements in different parameters after three months.But some factors include the scores’ change in total learning, retroactive interference score, forgetting rate,and net positive score were significantly higher in treatment groups at one-month and three-month follow-upscompared to the placebo group. In contrast, word span and hit parameters had the same pattern of improvementin both groups.Conclusion: The herbal medication can have a satisfactory effect on eliminating post-mTBI memory dysfunctionwhile having no considerable adverse effects. The effect of these components can also be sustained after a twomonthtimeframe. These results may assist patients to have less mental involvement.
Ali Meshkini; Amir Ghorbani; Zahra Hasanpour Segherlou; Masoud Nouri-Vaskeh
Volume 9, Issue 4 , October 2021, , Pages 183-187
Abstract
Objective: To examine the GFAP and S100B ability in prevention unnecessary brain CT scan in mTBI and compare them with the single extremity fracture in orthopedic patients. Methods: In this prospective cohort study, two orthopedics patients’ groups and mTBI patients were studied to assess the biomarkers’ ...
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Objective: To examine the GFAP and S100B ability in prevention unnecessary brain CT scan in mTBI and compare them with the single extremity fracture in orthopedic patients. Methods: In this prospective cohort study, two orthopedics patients’ groups and mTBI patients were studied to assess the biomarkers’ ability in prevention unnecessary brain CT scan at the emergency setting. There were 40 orthopedics’ patients with single extremity fracture and 41 mTBI patients. Brain CT scans were done for all mTBI patients. Results: Brain CT scans showed no intracranial traumatic lesions. The median levels for S100B in the mTBI group was 14.8 (4.4-335.9) ng/L, and in orthopedic patients’ group was 13.3 (5-353.10) ng/L. Statistically significant differences were observed between both groups in S100B levels (p=0.006). The median Glial Fibrillary Acidic Protein (GFAP) levels in the mTBI patients’ group were 600 (400-16300) and in the orthopedic patients’ groups was 60 ng/L (300-14900). Statistically significant differences were observed between groups in GFAP (p=0.041). Conclusion: Our results showed that S100B and GFAP serum levels were significantly higher in patients with mTBI than in patients with a single limb fracture.
sina jelodar; Ahmad Pourrashidi; Abbas Amirjamshidi
Volume 7, Issue 4 , October 2019, , Pages 416-419
Abstract
Sheno-occipital diastasis happens more frequently in children and is accompanied with neural and vascular injuries leading to a high rate of mortality. We present a rare type of clival fracture in a 21 years old man who could survive without any deficit even though the fracture extended widely from left ...
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Sheno-occipital diastasis happens more frequently in children and is accompanied with neural and vascular injuries leading to a high rate of mortality. We present a rare type of clival fracture in a 21 years old man who could survive without any deficit even though the fracture extended widely from left Asterion to the right orbit accompanied by widespread damage of the skull base air sinuses in 3D CT scan. To the best knowledge of the authors, neither this type of fracture, nor the clinical presentation, has been reported in relevant literature.
Kam Lun Ellis Hon; Szewei Huang; Wai Sang Poon; Hon Ming Cheung; Patrick Ip; Benny Zee
Volume 7, Issue 3 , July 2019, , Pages 256-262
Abstract
Objective: To determine the mortality, morbidity, types of intracranial hemorrhages, and factors associated with length of stay (LOS) associated with accidental traumatic brain injury (TBI) at a pediatric intensive care unit (PICU) of a regional trauma center in an Asian city.Methods: This study is a ...
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Objective: To determine the mortality, morbidity, types of intracranial hemorrhages, and factors associated with length of stay (LOS) associated with accidental traumatic brain injury (TBI) at a pediatric intensive care unit (PICU) of a regional trauma center in an Asian city.Methods: This study is a retrospective review of types of head injury, mortality and morbidity demographics of patients admitted to a PICU with TBI. All patients with accidental TBI were included, namely road traffic injury (RTI) and fall, and their demographics compared. Non-accidental injuries (NAI) were excluded.Results: 95 children (78% males) were admitted to a PICU with RTI or falls from 2002 to 2017. They accounted for 3.7% of PICU admissions. Comparing with falls, victims of RTI were older (p<0.001) and more likely to suffer from skull fracture (p=0.017). There were 4 deaths with falls (6.8%) but none with RTI. Subarachnoid hemorrhages, extradural hemorrhages, the use of mechanical ventilation, inotropes and neurological supports were associated with longer LOS in PICU in these injuries (p<0.001).Conclusion: A longer PICU LOS is associated with extradural and subarachnoid hemorrhages, usage of inotropes, mechanical ventilation and neurological supports in falls and RTI. Three-quarters of victims are males. Preventive health education should be especially directed to boys to reduce severe TBI in this Asian city.
Ali Abdoli; Farshid Rahimi-Bashar; Saadat Torabian; Sepideh Sohrabi; Hamid Reza Makarchian
Volume 7, Issue 2 , April 2019, , Pages 124-129
Abstract
Objective: To investigate the safety and efficacy of simultaneous administration of nimodipine, progesterone, magnesium sulfate in patients suffering from severe traumatic brain injury (TBI).Methods: Overall, 90 patients with blunt head trauma who were admitted to the Besat hospital, Hamadan University ...
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Objective: To investigate the safety and efficacy of simultaneous administration of nimodipine, progesterone, magnesium sulfate in patients suffering from severe traumatic brain injury (TBI).Methods: Overall, 90 patients with blunt head trauma who were admitted to the Besat hospital, Hamadan University of Medical Sciences, Iran through the Emergency Department in 2017 to 2018 were randomly assigned to the study or control groups each containing 45 patients. In the study group, intravenous nimodipine 60 mg every 12 hours for 5 days, intramuscular progesterone 1 mg/kg daily for 5 days, and magnesium sulfate 5 grams stat followed by 2.5 grams every 4 hours for 21 days were administered. Daily GCS and jugular venous oxygen saturation (SjvO2) of the patients were measured on admission day (day 0) through hospitalization day 4 at the intensive care unit. Then, all patients were visited at three months after discharge.Results: The mean age of the patients was 31.4 ± 12.8 years including 59 (65.6%) men with no significant difference between the groups. The baseline GCS and SjvO2 of the patients were comparable in both groups, however, GCS of the patients in the study group were significantly higher in the next 4 hospitalization days compared to the controls. Whereas, the SjvO2 of the patients were not significantly different between the groups during these days. Three-month mortality rate of the patients in the study group was significantly lower than the three-month mortality rate of the patients in the control groups (22.2% vs. 42.2%, p=0.042).Conclusion: Administration of combined protocol of magnesium sulfide, progesterone and nimodipine may be safe and effective in patients suffering from severe TBI.Clinical Trial Registry: IRCT201210229534N2
Mohammad Safdari; Zohre Safdari; Masoud Pishjoo
Volume 6, Issue 4 , October 2018, , Pages 372-375
Abstract
Trauma, especially traumatic injuries due to car accidents are one of the causes of maternal and fetal mortality and morbidity during pregnancy. Fetus brain injuries are usually caused fetus death. We herein report a pregnant woman in 28 weeks of gestation. The fetus was found to be normal during in-hospital. ...
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Trauma, especially traumatic injuries due to car accidents are one of the causes of maternal and fetal mortality and morbidity during pregnancy. Fetus brain injuries are usually caused fetus death. We herein report a pregnant woman in 28 weeks of gestation. The fetus was found to be normal during in-hospital. At birth, the female neonate demonstrated developmental delay and neurological deficits (hypotonicity). Neuroimaging after birth revealed extreme dilatation of lateral ventricles, hypoplasia and aplasia of the brain. In 4 months, she had multiple morbidities including developmental delay, hypotonia, blindness, oropharyngeal dysphagia and simple partial seizure. Motor and response to stimulation was normal. Appropriate seatbelt usage can protect the fetus from sustaining severe intracranial injuries.
Shahram Paydar; Behnam Dalfardi; Bardia Zangbar-Sabegh; Hossein Heidaripour; Leila Pourandi; Alireza Shakibafard; Mehdi Tahmtan; Leila Shayan; Mohammad Hadi Niakan
Volume 6, Issue 1 , January 2018, , Pages 26-30
Abstract
Objective: To determine the predictive value of repeated abdominal ultrasonography in patients with multiple trauma and decreased level of consciousness (LOC).Methods: This prospective cross-sectional study was conducted over a six-month period at Shahid Rajaee Trauma Hospital, Shiraz, Iran. We included ...
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Objective: To determine the predictive value of repeated abdominal ultrasonography in patients with multiple trauma and decreased level of consciousness (LOC).Methods: This prospective cross-sectional study was conducted over a six-month period at Shahid Rajaee Trauma Hospital, Shiraz, Iran. We included hemodynamically stable blunt abdominal trauma patients with a decreased LOC (Glasgow Coma Scale ≤ 13) who were referred to the neurosurgery ICU ward. Included cases underwent 1 contrast-enhanced CT scan and two-time ultrasonographic study of the abdomen with an interval of 48 hours. The diagnostic accuracy of the ultrasonography was determined according to the CT-scan results.Results: Overall 80 patients with mean age of 37.75 ± 18.67 years were included. There were 17 (21.3%) women and 63 (78.8%) men among the patients. Compared with the CT-Scan, the first ultrasonography showed a sensitivity of 60%, specificity of 80%, PPV of 16.60%, NPV of 96.80%, and a diagnostic accuracy of 70%. The same values for the second ultrasonographic study were 80%, 79%, 20%, 98%, and 79%, respectively. In 4 (5%) patients whose first ultrasonography and CT scan results were negative, the second ultrasonography was positive for injury.Conclusion: In patients with blunt trauma to the abdomen, when the only indication of abdominal CT scan is a decreased LOC, two ultrasonographic studies can replace a CT imaging.
Hadid Hamrah; Sarah Mehrvarz; Amir Mohammad Mirghassemi
Volume 6, Issue 1 , January 2018, , Pages 54-58
Abstract
Objective: To determine the frequency of the brain CT-scan findings in patients with mild traumatic brain injury (TBI) and scalp lacerations.Methods: This cross-sectional study was conducted during a 1-year period from March 2016 to March 2017 in Level I trauma center in Shiraz, Southern Iran. We included ...
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Objective: To determine the frequency of the brain CT-scan findings in patients with mild traumatic brain injury (TBI) and scalp lacerations.Methods: This cross-sectional study was conducted during a 1-year period from March 2016 to March 2017 in Level I trauma center in Shiraz, Southern Iran. We included all the adult patients (≥18 years) admitted to our emergency room with mild TBI (GCS on admission of 15) and scalp lacerations. All the patients underwent Brain CT-Scan and the scans were reviewed by two radiologists who were unaware of the patients’ clinical findings. The results are reported as proportions and frequencies.Results: Overall we included a total number of 94 patients with minimal TBI who had a scalp laceration on admission. The mean age of the patients was 30.78 ± 8.01 (ranging from 18 to 47) years. There were 58 (61.7%) men and 36 (38.3%) women among the patients. The most common finding of the Brain CT-Scan was subgaleal hematoma in 76 (80.9%) patients followed by base skull base fracture in 7 (7.4%), linear skull fracture in 7 (7.4%), brain contusion in 3 (3.2%) and subdural hematoma in 1 (1.1%). Conclusion: The results of the current study indicate that scalp lacerations are associated with intracranial injuries in about 20% of the patients with mild TBI. Thus brain CT-scan is recommended in all the patients with mild TBI and scalp lacerations.
Fariborz Ghaffarpasand; Maryam Dehghankhalili
Volume 5, Issue 2 , April 2017, , Pages 67-69
Giovanni Grasso; Iype Cherian
Volume 4, Issue 3 , July 2016, , Pages 119-120
Luis Rafael Moscote-Salazar; Andres M. Rubiano; Hernando Raphael Alvis-Miranda; Willem Calderon-Miranda; Gabriel Alcala-Cerra; Marco Antonio Blancas Rivera; Amit Agrawal
Volume 4, Issue 1 , January 2016, , Pages 8-23
Abstract
Traumatic brain injury is a leading cause of death in developed countries. It is estimated that only in the United States about 100,000 people die annually in parallel among the survivors there is a significant number of people with disabilities with significant costs for the health system. It has been ...
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Traumatic brain injury is a leading cause of death in developed countries. It is estimated that only in the United States about 100,000 people die annually in parallel among the survivors there is a significant number of people with disabilities with significant costs for the health system. It has been determined that after moderate and severe traumatic injury, brain parenchyma is affected by more than 55% of cases. Head trauma management is critical is the emergency services worldwide. We present a review of the literature regarding the prehospital care, surgical management and intensive care monitoring of the patients with severe cranioecephalic trauma.
Luis Rafael Moscote-Salazar; Nasly Zabaleta-Churio; Gabriel Alcala-Cerra; Andres M. Rubiano; Willem Guillermo Calderon-Miranda; Hernando Raphael Alvis-Miranda; Amit Agrawal
Volume 4, Issue 1 , January 2016, , Pages 58-61
Abstract
Chiari malformation Type I (CM-I) is a congenital disorder, which is basically a tonsillar herniation (≥ 5 mm) below the foramen magnum with or without syringomyelia. The real cause behind this malformation is still unknown. Patients may remain asymptomatic until they engender a deteriorating situation, ...
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Chiari malformation Type I (CM-I) is a congenital disorder, which is basically a tonsillar herniation (≥ 5 mm) below the foramen magnum with or without syringomyelia. The real cause behind this malformation is still unknown. Patients may remain asymptomatic until they engender a deteriorating situation, such as cervical trauma. The objective of this case report is to give a broad perspective on CM-I from the clinical findings obtained in a patient with asymptomatic non-communicating syringomyelia associated with a CM-I exacerbated within 2 years of a TBI, and to discuss issues related to that condition.
Saber Ghaffari-fam; Ehsan Sarbazi; Amin Daemi; Mohamadreza Sarbazi; Lachin Riyazi; Homayoun Sadeghi-Bazargani; Ali Allahyari
Volume 3, Issue 3 , July 2015, , Pages 104-110
Abstract
Objective: To describe the epidemiological and clinical characteristics of fall injuries in East Azerbaijan, Iran.Methods: This cross-sectional study was based on Hospital Information System (HIS) data for patients referred to the Imam Reza Hospital between 2008 and 2013. We recorded the demographic ...
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Objective: To describe the epidemiological and clinical characteristics of fall injuries in East Azerbaijan, Iran.Methods: This cross-sectional study was based on Hospital Information System (HIS) data for patients referred to the Imam Reza Hospital between 2008 and 2013. We recorded the demographic characteristics and epidemiological patterns of patients who were admitted to our center due to fall injuries. To standardize the reports the International Classification of Diseases (ICD), the International Classification of Diseases 9 Clinical Modification (ICD-9-CM)was used. Equally, the hospitalization period and number, admission ward, and the final status of victims after discharge from the hospital were extracted from the HIS.Results: Overall we included a total number of 3397 patients with mean age of 39.2±22.7 years. There were 2501 (73.6%) men among the patients. Long bone fracture (48.1%) and intracranial injury (24.2%) were the most frequent injuries among fall injury victims. Operations on spinal cord and spinal canal structures (12.0%), Operations on nose (11.6%) were the most common operations being performed in these patients. The survival was significantly lower in patients with age more than 60 years when compared to other age groups (p=0.001).The survival rate was significantly lower in age group of >60 years, compared to other age groups (p=0.001).Conclusion: Given the high rate of fall injuries and death among the elderly that increases with age, appropriate measures must be taken to control and prevent injuries while prioritizing the elderly.
Abdolkarim Rahmanian; Ali Haghnegahdar; Abdolvahab Rahmanian; Fariborz Ghaffarpasand
Volume 3, Issue 1 , January 2015
Abdolkarim Rahmanian; Ali Haghnegahdar; Abdolvahab Rahmanian; Fariborz Ghaffarpasand
Volume 2, Issue 4 , October 2014, , Pages 151-155
Abstract
Objective: To investigate the effects of intracranial pressure (ICP) monitoring on mortality rate and functional outcome of patients with severe traumatic brain injury (TBI).Methods: This was historical cohort study being performed in Nemazee hospital of Shiraz during a 4-year period (from 2006 to 2010) ...
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Objective: To investigate the effects of intracranial pressure (ICP) monitoring on mortality rate and functional outcome of patients with severe traumatic brain injury (TBI).Methods: This was historical cohort study being performed in Nemazee hospital of Shiraz during a 4-year period (from 2006 to 2010) including those patients with severe TBI who had undergone care based on ICP monitoring (case group) or clinical evaluation (control group).Patients and controls were matched regarding the age, sex, initial GCS, initial pupils, and CT findings. The functional outcome, complications and mortality rate were recorded and compared between those who underwent ICP monitoring and those who did not.Results: There was no significant difference between two study groups regarding the baseline characteristics. The rate of meningitis was significantly higher in those who underwent Ventriculostomy and ICP monitoring when compared to those who were managed without ICP monitoring. [14 (23.3%) vs. 7 (11.6%); p=0.041]. We found that the mortality rate (28.3% vs. 11.6%; p=0.172) as well as the frequency of persistent vegetative state (5.0% vs. 5.0%; p=0.998) were comparable between two study groups. However the frequency of severe disability was higher in control group compared to case group (26.7% vs. 15.0; p=0.046). In the same way, the frequency of good recovery (26.7% vs. 15.0; p=0.046) and favorable outcome (51.7% vs. 33.3%; p=0.021) was significantly higher in case group.Conclusion: Care based on ICP monitoring in patients with severe TBI was associated with increased frequency of good recovery and favorable outcome and decreased frequency of moderate disability. However higher meningitis rate was associated with Ventriculostomy and ICP monitoring.
Mousa Taghipour; Nima Derakhshan; Fariborz Ghaffarpasand
Volume 2, Issue 4 , October 2014, , Pages 166-169
Abstract
Syringobulbiais very rare condition defined as slit-like fluid cavity in the brain stem. Several conditions have been reported to be associated with syringobulbia including neoplasms, spinal cord traumas or lesions such as tethered cord, hind-brain herniation, infections such as meningitis and in isolation.Although ...
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Syringobulbiais very rare condition defined as slit-like fluid cavity in the brain stem. Several conditions have been reported to be associated with syringobulbia including neoplasms, spinal cord traumas or lesions such as tethered cord, hind-brain herniation, infections such as meningitis and in isolation.Although post-traumatic syringomyelia has been wieldy described previously, traumatic brain injury has not been reported as the mechanism and etiology of isolated syringobulbia. We herein report a 24-year old man with previous history of severe traumatic brain injury who presented with recent onset inability to walk or coordinate movements, ataxia, dysphonia, dysarthria, bilateral third nerve palsy with fixed dilated pupils and eyes deviated outward and downward.He was further diagnosed to have isolated syringobulbia extending to upper pons and lower midbrain.Isolated post-traumatic syringobulbia is extremely rare condition presenting insidiously with cranial nerve palsies, ataxia and dysarthria.
Fariborz Ghaffarpasand; Ali Razmkon; Hosseinali Khalili
Volume 2, Issue 3 , July 2014, , Pages 101-102
Willem Guillermo Calderon-Miranda; Hernando Raphael Alvis-Miranda; Gabriel Alcala-Cerra; Andres M Rubiano; Luis Rafael Moscote-Salazar
Volume 2, Issue 3 , July 2014, , Pages 130-132
Abstract
Traumatic basal ganglia hematoma is a rare condition defined as presence of hemorrhagic lesions in basal ganglia or adjacent structures suchas internal capsule, putamen and thalamus. Bilateral basal ganglia hematoma are among the devastating and rare condition. We herein report a 28-year old man, a ...
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Traumatic basal ganglia hematoma is a rare condition defined as presence of hemorrhagic lesions in basal ganglia or adjacent structures suchas internal capsule, putamen and thalamus. Bilateral basal ganglia hematoma are among the devastating and rare condition. We herein report a 28-year old man, a victim of car-car accidentwho was brought to our surgical emergency room by immediate loss of consciousness and was diagnosed to have hyperdense lesion in the basal ganglia bilaterally, with the presence of right parietal epidural hematoma. Craniotomy and epidural hematoma drainage were considered, associated to conservative management of gangliobasal traumatic contusions. On day 7 the patient had sudden neurologic deterioration, cardiac arrest unresponsive to resuscitation. Management of these lesions is similar to any other injury in moderate to severe traumatic injury. The use of intracranial pressure monitoring must be guaranteed.
Shahram Paydar; Hosseinali Khalili; Seyed Mohsen Mousavi
Volume 2, Issue 3 , July 2014, , Pages 136-137
Hernando Raphael Alvis-Miranda; Sandy Zuleica Navas-Marrugo; Robert Andrés Velasquez-Loperena; Richard José Adie-Villafañe; Duffay Velasquez-Loperena; Sandra Milena Castellar-Leones; Gabriel Alcala-Cerra; Juan Camilo Pulido-Gutiérrez; Javier Ricardo Rodríguez-Conde; María Fernanda Moreno-Moreno; Andrés M. Rubiano; Luis Rafael Moscote-Salazar
Volume 2, Issue 2 , April 2014, , Pages 65-71
Abstract
ABSTRACTObjective: To determine the effects of glycemic level on outcome patients with traumatic brain injury.Methods: From September 2010 to December 2012, all medical records of adult patients with TBI admitted to the Emergency Room of Laura Daniela ...
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ABSTRACTObjective: To determine the effects of glycemic level on outcome patients with traumatic brain injury.Methods: From September 2010 to December 2012, all medical records of adult patients with TBI admitted to the Emergency Room of Laura Daniela Clinic in Valledupar City, Colombia, South America were enrolled. Both genders between 18 and 85 years who referred during the first 48 hours after trauma, and their glucose level was determined in the first 24 hours of admission were included. Adults older than 85 years, with absence of Glasgow Coma Scale (GCS) score and a brain Computerized Tomography (CT) scans were excluded. The cut-off value was considered 200 mg/dL to define hyperglycemia. Final GCS, hospital admission duration and complications were compared between normoglycemic and hyperglycemic patients.Results: Totally 217 patients were identified with TBI. Considering exclusion criteria, 89 patients remained for analysis. The mean age was 43.0±19.6 years, the mean time of remission was 5.9±9.4 hours, the mean GCS on admission was 10.5±3.6 and the mean blood glucose level in the first 24 hours was 138.1±59.4 mg/dL. Hyperglycemia was present in 13.5% of patients. The most common lesions presented by patients with TBI were fractures (22.5%), hematoma (18.3%), cerebral edema (18.3%) and cerebral contusion (16.2%). Most of patients without a high glucose level at admission were managed only medically, whereas surgical treatment was more frequent in patients with hyperglycemia (p=0.042). Hyperglycemia was associated with higher complication (p=0.019) and mortality rate (p=0.039). GCS was negatively associated with on admission glucose level (r=0.11; p=0.46).Conclusion: Hyperglycemia in the first 24-hours of TBI is associated with higher rate of surgical intervention, higher complication and mortality rates. So hyperglycemia handling is critical to the outcome of patients with traumatic brain injury.
Hosseinali Khalili; Nima Derakhshan; Zahed Malekmohammadi; Fariborz Ghaffarpasand
Volume 2, Issue 2 , April 2014, , Pages 92-95
Abstract
Mycotic aneurysm of external carotid artery is extremely rare. We herein report a case of external carotid artery (ECA) aneurysm following severe traumatic brain injury. A 24-year-old man with severe traumatic brain injury (TBI) following a car accident was referred to Rajaee Trauma Center Emergency ...
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Mycotic aneurysm of external carotid artery is extremely rare. We herein report a case of external carotid artery (ECA) aneurysm following severe traumatic brain injury. A 24-year-old man with severe traumatic brain injury (TBI) following a car accident was referred to Rajaee Trauma Center Emergency Room affiliated to Shiraz University of Medical Sciences in Shiraz, Iran. He underwent ventriculostomy on arrival for intracerebral pressure (ICP) monitoring and for a second time due to hydrocephalus following decompressive craniectomy. He developed fulminant meningitis and ventriculitis during his hospital course. A bulged pulsatile lesion under the frontotemporal scalp resulted into the suspicion to underlying vascular pathology. Six-vessel angiography of brain was done which revealed mycotic aneurysm of external carotid artery. The patient underwent a two-week course of a combination of intravenous antibiotics. Follow-up angiography was performed which confirmed successful treatment of mycotic aneurysm of ECA. Mycotic aneurysm of ECA is extremely rare. To our knowledge, this is the first report of mycotic aneurysm of ECA following severe TBI which was successfully treated with antimicrobial therapy.